Organic Bioelectronic Device To Record And Transmit Brain Signals Plus Provide Power


A technical paper titled “Integrated internal ion-gated organic electrochemical transistors for stand-alone conformable bioelectronics” was published by researchers at Columbia University and Columbia University Medical Center.


“Organic electronics can be biocompatible and conformable, enhancing the ability to interface with tissue. However, the limitations of speed and integration have, thus far, necessitated reliance on silicon-based technologies for advanced processing, data transmission and device powering. Here we create a stand-alone, conformable, fully organic bioelectronic device capable of realizing these functions. This device, vertical internal ion-gated organic electrochemical transistor (vIGT), is based on a transistor architecture that incorporates a vertical channel and a miniaturized hydration access conduit to enable megahertz-signal-range operation within densely packed integrated arrays in the absence of crosstalk. These transistors demonstrated long-term stability in physiologic media, and were used to generate high-performance integrated circuits. We leveraged the high-speed and low-voltage operation of vertical internal ion-gated organic electrochemical transistors to develop alternating-current-powered conformable circuitry to acquire and wirelessly communicate signals. The resultant stand-alone device was implanted in freely moving rodents to acquire, process and transmit neurophysiologic brain signals. Such fully organic devices have the potential to expand the utility and accessibility of bioelectronics to a wide range of clinical and societal applications.”

Find the technical paper here. Published: July 2023.

Cea, C., Zhao, Z., Wisniewski, D.J. et al. Integrated internal ion-gated organic electrochemical transistors for stand-alone conformable bioelectronics. Nat. Mater. (2023). https://doi.org/10.1038/s41563-023-01599-w.

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